Stage 2 Breast Cancer Treatment Options

Medically Reviewed by Dr. K on 26 March 2021

Stage II Breast Cancer Treatment Options

The disease is in the breast and may have spread to surrounding lymph nodes in stage 2 breast cancer. The cancer is still localised inside the breast and, in some instances, nearby lymph nodes at this time. Several treatments can be beneficial. It’s possible that you’ll use a combination of them.


Surgery: Surgery is common. Smaller lesions can be treated with a breast-conserving operation, also known as a lumpectomy, in which only the tumour and any surrounding tissue are extracted. Larger tumours may necessitate a mastectomy, which involves the removal of the breast. The surgeon would most likely remove any lymph nodes in this situation. You can opt to get breast reconstruction surgery after a mastectomy.

Radiation therapy: A lumpectomy is normally followed by radiation therapy. It has the ability to destroy cancer cells that were missed during treatment. Radiation can be given to certain people who have a mastectomy, particularly if the tumour is huge or there are cancer cells in the lymph nodes.

Chemotherapy:  Chemotherapy after treatment may aid in the destruction of any cancer cells that were missed during surgery. To shrink a tumour, several patients get chemotherapy before surgery. If it succeeds, the tumour will shrink to the point that it can be removed with a lumpectomy.

Chemotherapy may be administered in a variety of forms. You can take pills or drink liquids, but most medications are inserted directly into the bloodstream. Depending on the method of procedure, it can be administered in stages to enable the body time to recover.

Hormone therapy: Women with hormone receptor-positive cancer can benefit from hormone therapy after surgery. This suggests that the cancer needs hormones to thrive. Medications may stop the hormones from reaching the tumour. Tamoxifen (Tamoxifen) is used by all women, while anastrozole (Arimidex), exemestane (Aromasin), and letrozole (Femara) are used by postmenopausal women. Some oestrogen receptor antagonists for metastatic breast cancer include fulvestrant (Faslodex) and toremifene (Fareston).

Women who haven’t achieved menopause may wish to have their ovaries removed in order to prevent them from producing hormones that encourage cancer growth. They may also take a medication to avoid their ovaries from producing hormones, such as goserelin (Zoladex) or leuprolide (Lupron).

Biological therapy: Biological therapy is a relatively recent treatment option. An abundance of a protein known as HER2 allows breast cancer to grow rapidly in around 25% of people with the disorder. Women with HER2-positive cancer are treated with ado-trastuzumab emtansine (Kadcyla), lapatinib (Tykerb), neratinib (Nerlynx), pertuzumab (Perjeta), and trastuzumab (Herceptin). They will make certain chemotherapy more successful by preventing this protein from causing cancer to spread. It’s sometimes paired with chemotherapy.

Clinical trials: Many women with stage 2 breast cancer will participate in clinical trials. You may be able to get exposed to cutting-edge drugs if you participate in a clinical trial. Many potential therapies, including medications, procedures, and variations, are currently being tested in clinical trials. Keep in mind that every successful treatment we’ve seen so far began with a clinical study.


Referenced on 25.3.2021

  1. American Cancer Society: “Learn about Cancer: Breast Cancer."
  2. National Cancer Institute: “Breast Cancer."
  3. CDC: “Breast Cancer."
  4. “Breast Cancer Stages,” “IDC Type: Cribriform Carcinoma of the Breast,” “IDC Type: Medullary Carcinoma of the Breast,” “IDC Type: Mucinous Carcinoma of the Breast,” “IDC Type: Papillary Carcinoma of the Breast,” “IDC Type: Tubular Carcinoma of the Breast,” “Male Breast Cancer,” “Metastatic Breast Cancer,” “Molecular Subtypes of Breast Cancer,” “Phyllodes Tumors of the Breast,” “U.S. Breast Cancer Statistics”
  5. Cleveland Clinic: “Breast Cancer.”
  6. Breast Cancer Prevention Partners: “Breast Cancer Subtypes.”
  7. CDC: “Breast Cancer: How Is Breast Cancer Diagnosed?”
  8. American Cancer Society: “What Is Breast Cancer?”
  9. Association of Directors of Anatomic and Surgical Pathology: “Breast Cancer,” “Breast Cancer In-Situ.”
  10. National Cancer Institute: “Cancer Stat Facts: Female Breast Cancer.”
  11. Mayo Clinic: “Breast cancer.”

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