COVID Booster Doses Can Slow Down The Spread Of Omicron Variant Infection

COVID Booster Doses Can Slow Down The Spread Of Omicron Variant Infection
Source – Clinical Trials Arena

Omicron is incapable of evading the body’s second-line defences. Recent research demonstrates that a fundamental element of the immune system’s second-line defence – T cells – are highly effective in recognising and attacking the Omicron variant, preventing the majority of infections from progressing to critical illness.


COVID Booster Doses Can Slow Down The Spread Of Omicron Variant Infection

The following is an overview of many recent COVID-19 studies. They include research that requires more research to substantiate the conclusions and has not been verified by peer review.

Omicron is incapable of evading the body’s second-line defences. Recent research demonstrates that a fundamental element of the immune system’s second-line defence – T cells – are highly effective in recognising and attacking the Omicron variant, preventing the majority of infections from progressing to critical illness. 

Omicron’s mutations enable it to evade the body’s first line of defence against infection, antibodies. Other components of the immune response may still target Omicron, although there has been no indication of this until recently.

Researchers in South Africa exposed copies of the virus to T cells from volunteers who had received vaccines from Johnson & Johnson (JNJ.N) or Pfizer (PFE.N)/BioNTech (22UAy.DE) or who had not been vaccinated but developed their own T cells following infection with an earlier variant of the coronavirus.

Source - Al Jazeera

Despite Omicron’s extensive mutations and reduced susceptibility to neutralizing antibodies, the majority of T cell response, induced by vaccination or natural infection, cross-recognizes the variant," the researchers reported.

Well-preserved T cell immunity to Omicron is likely to contribute to protection from severe COVID-19," the researchers concluded, validating what South African physicians assumed first when the majority of patients with Omicron infections did not develop the major disease.

The “T" denotes the thymus, the organ in which the cells complete their development.

Boosters reduce the possibility of Omicron household transmission.

The likelihood of vaccinated individuals contracting the virus if a household member gets sick is approximately three to four times greater with Omicron than with Delta. However, recent research suggests that booster doses lessen that risk.

The researchers analysed transmission data from over 12,000 infected homes in Denmark, including 2,225 households infected with Omicron. In all, 6,397 secondary illnesses occurred in the week after the first infection in residence. 

After accounting for other risk factors, the incidence of viral transmission from person to person was around 2.6 times greater in Omicron homes than in Delta households, the researchers reported on Monday on medRxiv ahead of peer review. They discovered that booster-vaccinated individuals were roughly 3.7 times more likely to get sick in Omicron-infected families than in Delta-infected households.

However, when only Omicron-infected households were included, booster-vaccinated individuals were 56 percent less likely to get infected than non-booster-vaccinated individuals. Additionally, when booster-vaccinated individuals took the virus home for the first time, they were less likely to transmit it to others than unvaccinated and vaccinated but not boosted individuals.

Source – Reuters

Total
1
Shares
Previous Post
Midnight Dip Ritual On The New Year’s Eve Will Be Barred In Sabah

Midnight Dip Ritual On The New Year’s Eve Will Be Barred In Sabah

Next Post
Malaysia Records 36 New COVID Deaths And Two Brought In Dead Cases

Malaysia Records 36 New COVID Deaths And Two Brought In Dead Cases

Related Posts
Total
1
Share